Transmembrane Glycoprotein
Transmembrane Glycoprotein
Transmembrane glycoproteins are important components of cell membranes and are characterized by oligosaccharide chains covalently linked to polypeptide chains. Glycosylation sites are mainly located in their extracellular regions, achieved by N-linked glycosylation (linked to asparagine residues) or O-linked glycosylation (linked to serine or threonine residues). Sugar chains not only provide structural stability to proteins but also confer functional specificity. Many transmembrane glycoproteins are receptors, such as G protein-coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs). Most （clusters of differentiation）CD molecules are also transmembrane glycoproteins expressed on the surface of antigen-presenting cells[1][2].
References:
- [1]. L Franco, et al. The transmembrane glycoprotein CD38 is a catalytically active transporter responsible for generation and influx of the second messenger cyclic ADP-ribose across membranes. FASEB J. 1998 Nov;12(14):1507-20. [Content Brief]
- [2]. Kumi Oshima, et al. SHPS-1, a multifunctional transmembrane glycoprotein. FEBS Lett. 2002 May 22;519(1-3):1-7. [Content Brief]
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Transmembrane Glycoprotein Inhibitors
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Transmembrane Glycoprotein Agonists
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Transmembrane Glycoprotein Antagonists
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Transmembrane Glycoprotein Activators
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Transmembrane Glycoprotein Modulators
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Transmembrane Glycoprotein Ligands
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Transmembrane Glycoprotein Related Products (379)
Related Products (379)
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Cadherin Peptide, avian
0 ImagesCat. No.: HY-P1086CAS No.: 127650-08-2Cadherin Peptide, avian is a calcium-dependent glycoprotein. Cadherin Peptide, avian takes part in homophilic cell-cell adhesion and dose-dependently inhibits bovine brain microvessel endothelial cells (BBMECs) adhesion.
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Anti-Siglec-15/CD33L3 Antibody
0 ImagesCat. No.: HY-P990505Purity: 98.6674%The Anti-Siglec-15/CD33L3 Antibody is a human-derived antibody expressed in CHO cells, targeting Siglec-15/CD33L3. The Anti-Siglec-15/CD33L3 Antibody contains a huIgG1 heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 146.02 kDa. The isotype control for the Anti-Siglec-15/CD33L3 Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Anti-F3/Factor III/Tissue Factor/CD142 Antibody
0 ImagesCat. No.: HY-P990411Purity: 98.88%Anti-F3/Factor III/Tissue Factor/CD142 Antibody is a CHO-expressed human antibody targeting F3/Factor III/Tissue Factor/CD142. The Anti-F3/Factor III/Tissue Factor/CD142 Antibody has a huIgG4SP type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for the Anti-F3/Factor III/Tissue Factor/CD142 Antibody can be referred to as Human IgG4 kappa, Isotype Control (HY-P99003).
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Stalk peptide
0 ImagesCat. No.: HY-P10430Stalk peptide is a GPR110 activator. Stalk peptide is released from GPCR Autoproteolysis INducing domain by autocatalytic process and then Stalk peptide is inserted into the ligand-binding pocket of the receptor to activate the receptor. Stalk peptide can promote nerve growth and synaptic formation. Stalk peptide can be used to study neurodevelopmental and neurodegenerative diseases.
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Anti-CD63 Antibody
0 ImagesCat. No.: HY-P991929
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Anti-Mouse RGMb Antibody (307.9D1)
0 ImagesCat. No.: HY-P990164Anti-Mouse RGMb Antibody (307.9D1) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse RGMb. Anti-Mouse RGMb Antibody (307.9D1) blocks RGMb binding to PD-L2. Anti-Mouse RGMb Antibody (307.9D1) can be used for the researches of cancer inflammation and immunology, such as acute myeloid leukemia (AML) and graft versus-host disease (GVHD).
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NSC 121182
0 ImagesCat. No.: HY-180492CAS No.: 24807-84-9NSC 121182 is a compound selected from NCI Diversity Set II by structure-based virtual screening. NSC 121182 can be used to study the Vitronectin-uPAR interaction. NSC 121182 can be used for cancer research.
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Anti-Mouse TIM-4 Antibody (RMT4-54)
0 ImagesCat. No.: HY-P990152Anti-Mouse TIM-4 Antibody (RMT4-54) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse TIM-4. Anti-Mouse TIM-4 Antibody (RMT4-54) reacts with mouse T cell immunoglobulin and mucin domain 4 (TIM-4) and blocks TIM-4 signaling. Anti-Mouse TIM-4 Antibody (RMT4-54) inhibits phagocytosis of apoptotic cells. Anti-Mouse TIM-4 Antibody (RMT4-54) can be used for the researches of immunology and metabolic disease.
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Anti-CD69 Antibody
0 ImagesCat. No.: HY-P990357
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Anti-NRG1 Antibody
0 ImagesCat. No.: HY-P992016
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Anti-CD81 Antibody
0 ImagesCat. No.: HY-P991933
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AT003
0 ImagesCat. No.: HY-P991575AT003 is a humanized monoclonal antibody targeting EpCAM/TROP1/CD326. AT003 can be used for synthesis of ADC.
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Anti-Mouse TIGIT Antibody (10A7)
0 ImagesCat. No.: HY-P991111Purity: 98.37%
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Anti-Mouse NKG2D/CD314 Antibody (HMG2D)
0 ImagesCat. No.: HY-P990804Anti-Mouse NKG2D/CD314 Antibody (HMG2D) is an Armenian hamster-derived IgG antibody inhibitor, targeting to mouse NKG2D/CD314. Anti-Mouse NKG2D/CD314 Antibody (HMG2D) can block NKG2D. Anti-Mouse NKG2D/CD314 Antibody (HMG2D) can be used for the researches of cancer, infection, inflammation and immunology, such as B16F10 tumor, colitis and L. major parasites and lymphocytic choriomeningitis virus (LCMV) co-infection.
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AT1412
0 ImagesCat. No.: HY-P991896Synonyms: AT14-012AT1412 is a CD9-binding antibody. AT1412 binds to the tetraspanin protein CD9 and modulates CD9 function by enhancing T cell adhesion to endothelial cells (HUVECs) and transendothelial migration. AT1412 binds to B-ALL cell lines but not to T-ALL. AT1412 induces antibody-dependent cellular cytotoxicity in B-ALL cell lines. AT1412 binds to melanoma cells, B-ALL, gastric cancer, colorectal cancer, and pancreatic cancer cells [1] .
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Anti-Mouse CD122/IL-2Rβ Antibody (5H4)
0 ImagesCat. No.: HY-P990293Anti-Mouse CD122/IL-2Rβ Antibody (5H4) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse CD122/IL-2Rβ. Anti-Mouse CD122/IL-2Rβ Antibody (5H4) can inhibit IL-2. Anti-Mouse CD122/IL-2Rβ Antibody (5H4) can be used for the researches of cancer and immunology, such as hepatocellular carcinoma.
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Yinyanghuo C
0 ImagesCat. No.: HY-N13016CAS No.: 149182-47-8Yinyanghuo C is a prenylated flavonoid isolated from the leaves of Epimedium sagittatum. Yinyanghuo C increases the mRNA expression levels of endothelial cell markers and enhances cancer-associated angiogenesis in the 4T1 breast tumor-bearing model.
